Have 48 Hours or Less? Here’s Your Quick Guide to Santorini

Few islands have quite the same allure as Santorini, and no other island (Greek or otherwise) can lay claim to being the source of the legend of Atlantis, either. Santorini, or “Thera” in Greek, is most celebrated for the dramatic views of its volcanic caldera, formed during a massive eruption around 1646 B.C. — which was catastrophic then but makes for some of the world’s most ravishing scenery today.

Use 48 hours in Santorini wisely to both better comprehend and simply enjoy this exceptional Greek island beauty.

As always, before any trip check for any travel restrictions or closures before planning your vacation.

Friday

Relax poolside at Mystique, a Luxury Collection Hotel, Santorini. (Photo: Marriott International)

Whether you get to Santorini by airplane, cruise ship or ferry, chances are good your first stop after arrival will be in or around Fira, the bustling but pretty main town on the island. Stroll the whitewashed lanes and savor the views out over the caldera: Odds are you won’t be alone, but part of the magic of Santorini is the energy of people who are there, just like you, to marvel at this geographical wonder. So slow down, relax, have a coffee and maybe do a little island shopping.

It’s frankly hard to find a restaurant anywhere in Santorini that isn’t good, but for one that pairs amazing, largely locally sourced food (think homegrown tomatoes, fava beans and capers) with a fabulous caldera view, try one of the best: Argo Restaurant.

When it’s time to bed down, head toward the northern tip of the island and the highly photogenic village of Oia where you’ll want to rest your travel-weary head in a suite or villa with a view at the cliffside Mystique, a Luxury Collection Hotel, Santorini. Alternatively, choose a retreat tucked away within the medieval village of Megalohori, the enchanting Vedema, a Luxury Collection Resort, Santorini has evolved from a 400 year old wine cellar and a 100 year old mansion into an authentic, Cycladic styled property.

Saturday

Take a dip at the Red Beach. (Photo: Getty Images)

Now that you’ve (hopefully) acclimated yourself to the Santorini rhythm, it’s time for a history and culture fix. Luckily, you’re in the right place. A recommended first stop is Santorini’s small but excellent Archaeological Museum in Fira.

Among the artifacts on display are artful vases and amphorae from the Archaic period, as well as the famous blue monkey frescoes, retrieved from your second cultural must, the ruins of the Minoan Bronze Age city of Akrotiri on the southern edge of the island.

At Akrotiri especially, prepare to be wowed: This is an active excavation site where you can wander among the twisting lanes of a settlement inhabited in the 16th century B.C. — that is, before Santorini’s infamous volcanic eruption buried it all in a mountain of ash. (Note: Whether you visit the museum in Fira or Akrotiri first is up to you, but both are truly musts.)

After a visit to Akrotiri, check out neighboring Kokkini (Red Beach), a spectacular place for a dip under the imposing reddish volcanic rocks.

Later, linger in Oia. If you’re feeling up to it, you can even walk along the clifftop path between there and Fira — add on about three hours if you do. Pop into the justly famous Atlantis Books and browse, and be sure to stick around for the sunset views high over the caldera for which Oia is most celebrated.

If you want to drink or dine at a private oasis set in a landscape awash with green and natural vegetation, look no further than NOŪS Pool Restaurant and Bar at NOŪS Santorini, a Member of Design Hotels™. Located near the center of the island, this haven of calm makes the perfect backdrop for relaxing evening.

Sunday

Catch the sunset over Oia. (Photo: Getty Images)

By Sunday, you might want to relax and do nothing — a highly acceptable activity in this corner of the Aegean — or perhaps explore some other aspects of Santorini’s heritage, which extends to the culinary realm, as well. In fact, thanks to the island’s rich volcanic soil, the cherry tomatoes grown here are famously tasty. Learn more about them at the Tomato Industrial Museum.

Santorini’s volcanic soil has also helped nurture the vineyards growing the grapes that make assyrtiko and other esteemed white wine island varietals; pop into virtually any winery you see outside of the towns for a tasting.

You could opt for something completely different, such as a mini-cruise around the caldera (there are many companies offering cruises of varying duration), or explore more of the fetching Santorini coastline by hitting the beach.

Kamari Beach is a black sand beach near the ruins of ancient Thera, an evocative archaeological site situated on a steep ridge overlooking the sea. South of these ruins, Perissa is another beach renowned for its black volcanic sand.

Take in one more sunset stroll back in Fira or Oia; then, time permitting, enjoy a memorable meal with a stunning view over sea and sky at Vatanee located in Domes Novos Santorini, Autograph Collection. If you’re feeling somewhat bewitched by it all, worry not: That’s just Santorini working its usual, timeless magic.

Published: April 04, 2025